Medication Safety In Pregnancy And Breastfeeding – The ConcePTION Big Data And Biobank Project

Pixabay License | Source:  PublicDomainPictures , no changes made.
Advertisement

A landmark public-private partnership called ConcePTION was recently awarded a 5-year grant by the European Innovative Medicines Initiative (IMI2) to tackle many of the research gaps related to medicine used by pregnant and breastfeeding women.

ConcePTION is a 5-year, €28.6 million project supported by the Innovative Medicines Initiative (IMI), a public-private partnership between the European Union and the European pharmaceutical industry. The pharmaceutical industry contributes €13.3 million to the project through in-kind contributions, whereas the European Commission funds €15.3 million in cash. The consortium, comprising close to 200 researchers, is governed and managed by a balanced 50/50 split of public and private partners, and is jointly led by Novartis and the University Medical Center Utrecht.

Up to 90% of women are exposed to a prescription medication at some point during their pregnancy. Women and their healthcare providers face difficult choices before, during, and after pregnancy, due to a widespread lack of information. Physicians help women to select the safest medication, but they seldom have robust evidence to allow them to make informed decisions.

Advertisement The Springer Shop

Today, only about 5% of medications have adequate safety information on use in pregnant or breastfeeding women. Obtaining reliable safety information after a medicine is on the market can take 20 or more years to collect.

ConcePTION will form a networked system bringing together the major data sources dispersed across Europe to curate big data from routine patient care. ConcePTION will also create the first Europe-wide breast milk biobank for research purposes. From this the team will develop new models that can predict medication transfer into human breastmilk.

In this way, ConcePTION will create a trusted biomedical ecosystem that can efficiently, systematically, and ethically, generate reliable evidence-based information regarding the safety of medications used during pregnancy and breastfeeding. ConcePTION aims to provide that information in a form that is usable by both healthcare providers and women to facilitate informed decision making.

Source

  1. https://www.prnewswire.com/news-releases/conception-building-a-pan-european-ecosystem-for-generating-monitoring-and-providing-robust-information-on-medication-safety-in-pregnancy-and-breastfeeding-300867205.html
Advertisement

David is a consultant/medical writer for a number of ongoing healthcare initiatives including for Athla LLC/ HealthLabs, a discovery automation company for Big Data leveraging Big Compute. He has a number of years experience in academic R&D and healthcare related projects including the fields of oncology and immunotherapy.