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Future Direction of Biobanking

Future Direction of Biobanking

Columns like this one is a great opportunity to share some thoughts with the biobanking community and get some feedback. This helps identifying those relevant to the biobankers and those that are not so relevant. Please continue to reach...

C-BIG Repository: World’s Leading Open Access Biobank of Neurological Disorders

The Neuro (Montreal Neurological Institute-Hospital) has launched the Clinical Biospecimen Imaging and Genetic (C-BIG) Repository, one of the largest biorepositories of neurological disorders in the world, as an open access resource for the global scientific community. The C-BIG Repository...

Water On The Brain: A Biobank Of Failed Shunt Devices

Hydrocephalus, otherwise known as water on the brain, is a condition where cerebrospinal fluid (CSF) accumulates within the brain. Hydrocephalus that occurs in childhood has a frequency of about 1 person in 1100 within the USA. The surgical placement...

Recapitulating Pharmacology With Genetics

The medical term for heart rate over 100 beats per minute is tachycardia. The small molecule ivabradine reduces heart rate via specific inhibition of the pacemaker current. It is also used to alleviate chest pain (angina pectoris) and as...

Cell Biobanks Are Critical For Organoids, Organ-On-Chips, And Additive Manufacturing

While the original 2D cell culture methods remain indispensable for routine laboratory operations and biochemical analyses it has become increasingly clear that they do not accurately represent organ systems in the body. To fully understand a system or device...

Is The ACE Job–Exposure Matrix More Broadly Applicable In The UK Biobank?

A job-exposure matrix (JEM) is an approximation of potential health hazard exposures used in occupational epidemiological studies. The matrix of exposure levels to toxic or potentially harmful agents is extrapolated from occupational titles. As workplaces and individual circumstances vary...

A Prototype Sample Locator For The German Biobank Alliance

As of 2020, the German Biobank Alliance (GBA) consists of 20 biobanks distributed across the country. The GBA is coordinated by the German Biobank Node (GBN) organization. Researchers wishing to access biosamples within the GBA biobanks currently directly contact...

Design And Testing Of A Dendritic Cell Therapy Vaccine Against HIV-1

Infection with the human immunodeficiency virus 1 (HIV-1) is now a manageable condition, rather than a death sentence, as it once was. This is largely due to the development and commercialization of antiretroviral therapy (ART). In 2010 the annual...

Migraine Medication Overuse Prediction Using Machine Learning

The underlying mechanism of migraine headache is still poorly understood and is likely results due to a combination of genetics and “trigger” events. The patient population is therefore highly diverse and no one treatment fits all migraine sufferers. The...

The Shanghai Suburban Adult Cohort And Biobank

The population of China is estimated to be 1.41 billion people, at least 16.87 million of whom live in the Shanghai metropolitan area. The urban landscape has undergone rapid development. In 1990 the percentage of the Chinese population living...

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