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Sample Processing Has Important Consequences For Single Cell Sequencing Studies

Single-cell transcriptomics is a relatively new technology that reads and reports the gene expression profile of individual cells by simultaneously measuring the mRNA concentration of all the cell’s genes. This is achieved through microfluidic chip single cell isolation, barcoding, cDNA...

Biobank Study Of Functional Lung Impairment And Lung Cancer Risk

Globally, cancer of the lung is the most common cause of cancer related mortality. It is also the most commonly diagnosed. Tobacco smoke is a well-known risk factor for the development of lung cancer. Smoking leads to lung impairment and...

Potential Targets For Opioid Addiction Treatment Uncovered By GWAS

The USA is in the midst of an opioid addiction crisis with overdoses having killed 47,600 people in 2017, according to the Centers for Disease Control and Prevention (CDC). Opioids such as OxyContin® and Vicodin® are used in pain medications...
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Dynamic Consent In Biobanking Using Dwarna – A Blockchain Solution

A research team with senior author Jean-Paul Ebejer from the Centre for Molecular Medicine and Biobanking at the University of Malta has created a blockchain solution for dynamic consent in biobanking called Dwarna. They published their...

Multinational Kids-DOTT Trial Of Anticoagulant Therapy For Venous Thromboembolism

Enrollment has completed for a landmark randomized clinical trial at Johns Hopkins All Children’s on the duration of anti-clotting medication (anticoagulant) therapy for venous thromboembolism (VTE) in patients under 21 years old — the Kids-DOTT trial. A multinational biobank of...

New Alzheimer’s Disease Organoids Enable Drug Discovery

Scientists at Scripps Research have reported for the first time that Alzheimer’s patient-derived stem cells, which are engineered to become “mini-brains” for lab research. The organoids manifest excessive seizure-like electrical activity just like human patients with the disease, enabling drug discovery.

The Gift Of Life Marrow Registry To Receive Advocacy Award At World Stem Cell...

The formal ceremony of the 2020 Stem Cell and Regenerative Medicine Action Awards will take place at a gala reception and dinner on January 23, during the 15th annual World Stem Cell Summit (WSCS) at the Hyatt...

Age And Long-Term Conditions Are Linked To Accelerated Loss Of Skeletal Muscle

A new study led by the AGE Research Group, Newcastle University and Newcastle upon Tyne NHS Foundation Trust, UK, describes the prevalence of sarcopenia in the UK Biobank, a large sample of men and women aged 40–70...

The Consortium On Vulnerability To Externalizing Disorders And Addictions – cVEDA

The Consortium on Vulnerability to Externalizing Disorders and Addictions (cVEDA) is a proposed multi-site, international, collaborative, cohort study based in India. It aims to examine the interactions of environmental exposures, and genomic influences on neurodevelopmental trajectories and...

Take A Second Look – Variation In Some UK Biobank Genes May Not Be...

Recently it has been revealed that thousands of gene variants in the UK Biobank (UKB) exome data have been overlooked due to errors in sequence processing. Unfortunately, two independent UKB sequence processing pipelines contained errors that effect...

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