LATEST ARTICLES

Water On The Brain: A Biobank Of Failed Shunt Devices

Hydrocephalus, otherwise known as water on the brain, is a condition where cerebrospinal fluid (CSF) accumulates within the brain. Hydrocephalus that occurs in childhood has a frequency of about 1 person in 1100 within the USA. The...

Recapitulating Pharmacology With Genetics

The medical term for heart rate over 100 beats per minute is tachycardia. The small molecule ivabradine reduces heart rate via specific inhibition of the pacemaker current. It is also used to alleviate chest pain (angina pectoris)...

Cell Biobanks Are Critical For Organoids, Organ-On-Chips, And Additive Manufacturing

While the original 2D cell culture methods remain indispensable for routine laboratory operations and biochemical analyses it has become increasingly clear that they do not accurately represent organ systems in the body. To fully understand a system...

Biomarker Changes In Skin Keratinocytes Responsive To Blood Glucose

Biomarkers in the skin can reflect disease status in conditions as diverse as diabetes,  rheumatism, lung disease, and neurodegenerative diseases. In the case of diabetes, minimally invasive skin mounted glucose monitoring devices exist. Each device has its...

Autoscribe Informatics Invests in MIDAS to Aid Laboratory 4.0

Autoscribe Informatics, a leading global laboratory informatics provider, announced the latest release of the Matrix Instrument Data Acquisition System (MIDAS). This release continues the company’s commitment to helping their customers maximize the value of their laboratory informatics investment. By...

Is The ACE Job–Exposure Matrix More Broadly Applicable In The UK Biobank?

A job-exposure matrix (JEM) is an approximation of potential health hazard exposures used in occupational epidemiological studies. The matrix of exposure levels to toxic or potentially harmful agents is extrapolated from occupational titles. As workplaces and individual...

A Prototype Sample Locator For The German Biobank Alliance

As of 2020, the German Biobank Alliance (GBA) consists of 20 biobanks distributed across the country. The GBA is coordinated by the German Biobank Node (GBN) organization. Researchers wishing to access biosamples within the GBA biobanks currently...

Design And Testing Of A Dendritic Cell Therapy Vaccine Against HIV-1

Infection with the human immunodeficiency virus 1 (HIV-1) is now a manageable condition, rather than a death sentence, as it once was. This is largely due to the development and commercialization of antiretroviral therapy (ART). In 2010...

WTAP Gene Polymorphisms Modify Risk Of Hepatoblastoma

Hepatoblastoma is a form of cancer that accounts for 80% of childhood liver cancers, but only 1% of childhood cancers in total. It usually presents between birth and three years of age. As it is a relatively...

Leptin Associated With Cognitive Impairment In Older Adults Scheduled For Surgery

Adipokines are cytokines secreted by adipose (fat) tissue. Their existence was first noted in 1994, with the discovery of leptin. This cytokine is known to suppress hunger, but also promotes atherosclerosis, endothelial dysfunction and inflammation. Another adipokine,...