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An Organoid Model Of The Human Midbrain

In Parkinson’s disease dopaminergic neurons are irrecoverably lost from the midbrain resulting in slowed movement, tremors and other symptoms. Dopamine augmentation is the main treatment for Parkinson’s, however, there is no cure available that can reverse the symptoms, partly...

A Living Biobank Of Non-Small Cell Lung Cancer Organoids

Globally, cancer of the lung is the most common cause of cancer related mortality. It is also the most commonly diagnosed. 3D patient derived organoids provide a more faithful model of cancer than 2D in vitro cell culture and represent a model...

New Alzheimer’s Disease Organoids Enable Drug Discovery

Scientists at Scripps Research have reported for the first time that Alzheimer’s patient-derived stem cells, which are engineered to become “mini-brains” for lab research. The organoids manifest excessive seizure-like electrical activity just like human patients with the disease, enabling drug discovery. Scripps Research ranks...

New Papers Discuss The Science And Ethics Of Human Brain Organoids

Research involving the transplantation of human “mini-brains”—known as brain organoids—into animals to study disease can provide crucial insight’s into disease. Medical ethicist’s have raised a concern that must be considered. There is the possibility, however minute, that the grafted...

Crown Bioscience Teams Up With HUB To Launch Tumor Organoid Drug Development Platform

Crown Bioscience has launched a new tumor organoid drug development platform with the potential to significantly improve the predictivity and speed of preclinical drug discovery. Independently founded in 2006, Crown Bioscience, now a JSR Life Sciences company, a business unit of JSR Corporation,...

MIMETAS And Hubrecht Organoid Technologies Partner To Market Organoids-On-A-Chip

MIMETAS and Hubrecht Organoid Technologies (HUB) have entered into a strategic collaboration to market organoid models on a Chip. The agreement includes a license to MIMETAS to market HUB Organoids in an assay ready format, as well as a collaborative effort to...

A:Head Bio AG Incorporated To Use Cerebral Organoids For CNS Drug Discovery

a:head bio AG, an Austrian biotech company focused on the development of next generation therapeutics for the treatment of brain disorders based on human cerebral organoids has recently been incorporated. The new venture is based on groundbreaking technology developed at the Institute...

Proteostasis Therapeutics Contributes To HIT-CF Europe Cystic Fibrosis Organoid Drug Screens

Proteostasis Therapeutics, Inc., has announced that it has been invited to join the HIT-CF Europe, a pan European strategic initiative which seeks to validate a personalized therapy approach for cystic fibrosis (CF) patients with extremely rare genetic mutations. Founded in...

The Use of RFID in Biobanking: a Focus on Tracking and Storing Organoids

Radio-frequency identification (RFID) automatically identifies and tracks tags attached to objects. The tags can contain various electronically stored information. The advantage of RFID over a barcode is that the tags may be embedded within the tracked object, as the...

STEMCELL Technologies Licenses Inner Ear Organoid Culture Technique

The ability to hear music and keep balanced when upright is dependent on mechanosensory “hair cells” in the inner ear that convert vibrations into electrical signals . They are located inside the organ of Corti within the snail-shaped cochlea...

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