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Apolipoprotein E (APOE) Isoform Association With Aging In UK Biobank

The APOE (Apolipoprotein E) gene has three main isoforms known as APOE2, APOE3, and APOE4. The ε4 allele is thought to be the oldest, whereas ε2 is the most recently evolved. In the European ancestry population the frequency of...

Proteomic Study Of Alzheimer’s With ApoE4

Apolipoprotein E (APOE) is a 299 amino acid protein which can be induced by consuming foods rich in cholesterol. The APOE gene has three main alleles termed ε2-4, which are translated into the proteins ApoE2-4. Apolipoproteins play a role...

New Alzheimer’s Disease Organoids Enable Drug Discovery

Scientists at Scripps Research have reported for the first time that Alzheimer’s patient-derived stem cells, which are engineered to become “mini-brains” for lab research. The organoids manifest excessive seizure-like electrical activity just like human patients with the disease, enabling drug discovery. Scripps Research ranks...

New Research Into Impact Of Lifestyle On Alzheimer’s Disease Risk

New research reported at the Alzheimer's Association International Conference (AAIC) 2019 in Los Angeles, USA, suggests healthy lifestyle choices including healthy diet, exercise, and cognitive stimulation, may decrease risk of cognitive decline and dementia. The research suggests that lifestyle modifications may reduce risk...

Patent-Pending Biosensor And Method For Detecting Early Stage Alzheimer’s Developed

Scientists from Ruhr-Universität Bochum (RUB), in Germany have developed a test using two biomarkers that can detect Alzheimer’s (AD) at an early stage. The method was developed from samples banked from 61 disease control patients and 39 AD cases,...

Cytox To Make Use Of Mayo Clinic’s Alzheimer’s Biobank

Cytox is a precision medicine company with a focus on neurodegenerative disorders such as Alzheimer’s disease. The Cytox scientific and proprietary technology platform is being applied to the prediction of cognitive decline and neurodegenerative disorder risk. The Mayo Clinic is...

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