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Learning From Human Bile – A Machine Intelligence Approach

The digestive fluid called bile is made up of acids, salts, fats, and the pigment bilirubin, stored and concentrated in the gall bladder, and...

Serum Uric Acid Predicts Kidney Cancer Incidence

According to the US Surveillance, Epidemiology, and End Results program, the outlook for kidney cancer patients is generally favourable with an overall five year...

PALB2 May Be A Risk Locus For Ovarian Cancer

According to US Surveillance, Epidemiology, and End Results (SEER), overall, the five year survival rate for ovarian cancer is 49%, however for those aged...

Estrogen Receptor Isoforms Are Down-Regulated In Hepatocellular Carcinoma

Estrogen receptor alpha (ERα) translocates to the nucleus and induces gene expression upon activation. The estrogen receptor is a target of US Food and...

Markers Of “Immune Hot” Esophageal Adenocarcinoma

According to the US National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results Program (SEER), the incidence of adenocarcinoma of the esophagus (EAC) is...

A Ubiquitination Inhibitor Hakin-1 Potentially Has Efficacy In Colorectal Cancer

Hakai is a 491 amino acid E3 ubiquitin-protein ligase that forms a dimer if zinc is available. This allows Src tyrosine kinase dependant interaction...

Associations Between Chemicals And Colorectal Cancer

Cancer is a disease that is influenced by both extrinsic and genetic factors. These factors can be protective or deleterious. Gene-extrinsic factor interactions could...

Targeting CK1δ In Bladder Cancer

According to data from the US National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) program, the 5-year survival rates, 2000-2016, for invasive bladder...

Perspective On Cancer Biomarker Biobanks

Liquid biopsy is an area of immense opportunity for the early detection and screening of cancer. Suitable fluids include stool, blood, sputum, urine, and...

Genetically Predicted Iron Status Correlated With Risk Of Liver Cancer

Iron overload is a known risk factor for liver disease including liver cancer. The potential for iron overload to be a risk factor in...

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