Sample Processing Has Important Consequences For Single Cell Sequencing Studies

Single-cell transcriptomics is a relatively new technology that reads and reports the gene expression profile of individual cells by simultaneously measuring the mRNA concentration of all the cell’s genes. This is achieved through microfluidic chip single cell isolation, barcoding, cDNA...

How Safe Are Your Samples?

Plastic storage tubes are used in laboratories worldwide to store biological and chemical samples, the most typical resin used is Polypropylene. There are many types and grades of polypropylene that are selected either on cost, molding properties or specific...

Take A Second Look – Variation In Some UK Biobank Genes May Not Be...

Recently it has been revealed that thousands of gene variants in the UK Biobank (UKB) exome data have been overlooked due to errors in sequence processing. Unfortunately, two independent UKB sequence processing pipelines contained errors that effect...

351 Lymphoblastoid Cell Lines Added To NIA Aging Cell Repository At Coriell Institute

Hundreds of biological samples donated from individuals aged 90 years or older have been added to the National Institute on Aging’s (NIA) Aging Cell Repository, housed at the Coriell Institute for Medical Research. The samples, a total of 351 lymphoblastoid...

Maximize Sample Value Using MbioLIMS Biobanking®

Sponsored content brought to you by Biobanking and the connection to Industry and research is growing. The way biobanks are used and the scale of their importance to future health is being discussed around the world. Data, and how it is...

The Importance of Monitoring Biobanking Laboratory Storage

Sponsored content by Challenges with Storage for Biobanking The storage of highly sensitive materials is an important area to consider for Blood Banks, Tissue Banks, and Biobanks. There are many variables and parameters that must be diligently controlled and monitored at...

Biospecimen Quality in Clinical Research

Abstract Biospecimens form an integral part of many clinical research studies. The production of valid clinical data sets depends largely upon the quality of biospecimens utilized in the study. Annotations of biospecimens help unveil information related to disease prognosis, diagnosis,...

Biobanking Science: Storing Cells at Room Temperature

Cryopreservation is the gold standard method to store biospecimens in biobanking organizations. Cryopreservation usually involves flash freezing samples and storing them at ultra-low temperatures (-160°C to -190°C) to prevent chemical degradation. If biobanking scientists follow strict freezing...

Four-Part Mendelspod Podcast Series On Human Biospecimen Quality And Regulations

Scientist.com has announced the completion of a four-part podcast series on human biological samples and biobanking. The four guests offered thoughtful insights and ideas from an academic, pharmaceutical and small business perspective. The episodes were hosted by, and are...
Biobanked plasma samples had stable IL6 and CRP levels

Biobanking Science: How Storage Affects Inflammatory Biomarkers

Biobanking storage conditions can affect long-term sample quality and integrity1. A number of biomarkers are particularly sensitive to storage temperature and can degrade even when biobanked at -80°C. Furthermore, researchers often struggle with variable results from assays run in...

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