Biobanking Science: CRISPR Gene Editing to Treat Human Disease

This year has seen a flurry of good news about CRISPR gene editing clinical trials in human patients. CRISPR-Cas 9 is a gene editing tool capable of providing specific changes to genes in a wide range of animal models....
Biobanking and colorectal cancer tissues

Biobanking Science: Biobanking Samples for Colorectal Cancer

Colorectal cancer is the third most common cancer, affecting 1.8 million new patients and causing 862,000 deaths every year (1). Studies show that eating processed or red meat and drinking alcohol may increase the risk for colorectal cancer (2)....
CSF Biomarkers may help diagnose patients with neurological diseases

Biobanking Science: CSF Biomarkers for Neurological Diseases

Biobanks can help in the search for biomarkers to diagnose brain diseases. Neurological diseases can be difficult to diagnose as they may have overlapping symptoms. Furthermore, there are currently no diagnostic tests for diseases such as Amylotrophic lateral sclerosis...

Biobanking Science: Can Antivirals Treat Alzheimer’s Disease?

Alzheimer’s disease is the most common cause of dementia, affecting over 25 million people worldwide and costing more than US$400 billion a year (1). The number of Alzheimer’s patients is predicted to rise to over 60 million...
Intermittent dieting can help reverse obesity.

Biobanking Science: Treating Obesity With Intermittent Fasting

Obesity has reached epidemic proportions. Over 1.9 billion adults and 380 million children are now overweight or obese (1). These people are more likely to suffer from chronic life-threatening diseases such as heart disease, stroke, diabetes and cancer (1)....
Hypertrophic cardiomyopathy is a serious heart disease.

Biobanking Science: Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy is one of the most common inherited heart diseases, affecting 1:200 people (1). Patients with hypertrophic cardiomyopathy have thickened left ventricles which can lead to life-threatening complications such as arrhythmias, heart failure and sudden death (2). Hypertrophic...
Traumatic brain injury can increase the risk of neurodegenerative diseases.

Biobanking Science: Biomarkers for Traumatic Brain Injury

Traumatic brain injury has been in the news lately because even mild traumatic brain injury, or concussion, can increase the risk of developing neurodegenerative diseases like Parkinson’s disease (1). Many parents have understandably been worried about their children suffering...
chronic kidney disease patients may need transplant

Biobanking Science: Biobanks Tackle Chronic Kidney Disease

Chronic kidney disease is common. The prevalence of chronic kidney disease has rapidly increased over the past 20 years, and it now affects 13% of people around the world (1). Chronic kidney disease can be difficult to treat because...
gene therapy product retroviral vector

Biobanking Science: Safe Gene Therapy

Gene therapy has the potential to cure any disease caused by genetic mutations. For gene therapy to work, normal copies of genetic DNA, replacement messenger RNA or gene-editing constructs must be delivered to affected cells. Nucleic acids are rapidly...
metabolomics needs biobanks

Biobanking Science: Metabolomics Biobanks

Metabolomics, an important part of precision medicine, is the study of different metabolites in normal and disease states. Collecting, processing and storing samples for metabolomics studies presents unique challenges for biobanks. Metabolites are small (low molecular weight) and unstable molecules....

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