A New Blood Test Algorithm mPoA – Quantifying Biological Aging

People age at different rates determined by both their environment/ lifestyle and genetics. Biological aging is the gradual and progressive decline in body integrity that occurs over time eventually leading to loss of vitality or illness/ disability in some cases....

ALS Biomarker Study At Massachusetts General Sponsored By Mitsubishi Tanabe Pharma America

Mitsubishi Tanabe Pharma America, Inc. (MTPA) has announced a collaboration with the Massachusetts General Hospital (MGH) Neurological Clinical Research Institute (NCRI) to conduct a study designed to identify and measure specific biomarkers in people with amyotrophic lateral sclerosis (ALS).

Biobank Study Reveals New Gene Variants Implicated In Asthma

Asthma is a chronic condition that can sporadically effect breathing. People with the condition have narrowed inflamed airways, which produce excess mucus, restricting breathing. The “Dutch” hypothesis suggests that asthma may develop into COPD. According to the US Centers for...

CLOVER Study Of PDL1 In NSCLC Demonstrates PCR RNA Expression Analysis Not Equivalent To...

Programmed cell death ligand 1 (PDL1) is approved therapeutic target in lung cancer patients. PDL1 expression above a set threshold must be confirmed by companion immunohistochemistry (IHC) test in order for the patient to be eligible for...

Study Highlights Nutritional Biomarkers In Dementia

According to the World Health Organization (WHO), the global number of people living with dementia is set to triple to 150 million by 2050. The condition which involves cognitive decline and eventual death can affect people in ways they cannot...

Biobanking Teeth Could Help To Forecast Mental Health Problems

Teeth could serve as an actionable new tool capable of measuring the presence and timing of childhood adversity, a major risk factor for psychiatric and physical health concerns in the future. The novel approach is outlined in...

Genetically Predicted Iron Status Correlated With Risk Of Liver Cancer

Iron overload is a known risk factor for liver disease including liver cancer. The potential for iron overload to be a risk factor in other cancers was poorly understood. Susanna C. Larsson of the...

First Healthy Aging Data Release From 2570 Participants In The Medical Genome Reference Bank

The Medical Genome Reference Bank (MGRB) is planned to contain the whole genome sequences (WGS) of over 4000 elderly individuals with no reported history of cancer, cardiovascular disease, or neurodegenerative diseases until at least age 70.

Multinational Kids-DOTT Trial Of Anticoagulant Therapy For Venous Thromboembolism

Enrollment has completed for a landmark randomized clinical trial at Johns Hopkins All Children’s on the duration of anti-clotting medication (anticoagulant) therapy for venous thromboembolism (VTE) in patients under 21 years old — the Kids-DOTT trial. A multinational biobank of...

Biomarker Candidates For Dementia With Lewy Bodies Identified In Cerebrospinal Fluid

Besides Alzheimer’s disease (AD), Dementia with Lewy Bodies (DLB) is the second most common form of progressive dementia, accounting for up to 20% of cases. The main protein component of Lewy Bodies, which form in the nerve...

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