Biomarker Candidates For Dementia With Lewy Bodies Identified In Cerebrospinal Fluid

Besides Alzheimer’s disease (AD), Dementia with Lewy Bodies (DLB) is the second most common form of progressive dementia, accounting for up to 20% of cases. The main protein component of Lewy Bodies, which form in the nerve...

Perspective On Cancer Biomarker Biobanks

Liquid biopsy is an area of immense opportunity for the early detection and screening of cancer. Suitable fluids include stool, blood, sputum, urine, and others. This is aided by emerging technology which can allow the measurement of...

Measures Of Air Pollution And Associations With Biobank Data

Air pollution may influence brain volume. Total grey matter to white matter volumes are thought to be related to cognitive function or decline. Air pollution might affect total gray-matter and white-matter volumes which could be important in determining individual and...

Diabetes, Dyslipidemia and Hypertension In The Taiwan Biobank

Diabetes, dyslipidemia and hypertension have global prevalence rates of 8.5%, 38%, and 40%, respectively. Disease prevalence may be used as a proxy for disease incidence so it follows that population clusters with reduced disease prevalence may potentially represent individuals with...

CLOVER Study Of PDL1 In NSCLC Demonstrates PCR RNA Expression Analysis Not Equivalent To...

Programmed cell death ligand 1 (PDL1) is approved therapeutic target in lung cancer patients. PDL1 expression above a set threshold must be confirmed by companion immunohistochemistry (IHC) test in order for the patient to be eligible for...

Cigarette Associated Cardiovascular Disease And Inflammation In The Guangzhou Biobank

Cigarette smoking is the leading preventable cause of death (one in five deaths) in the United States. It is also highly prevalent in China, and globally. Sadly, 90% of all lung cancer deaths can be attributed to smoking. It also...

Genetically Predicted Iron Status Correlated With Risk Of Liver Cancer

Iron overload is a known risk factor for liver disease including liver cancer. The potential for iron overload to be a risk factor in other cancers was poorly understood. Susanna C. Larsson of the...

Impact Of Diet And Exercise On “Good Cholesterol” Levels In A Taiwanese Population

“Good cholesterol”, the common name for high-density lipoprotein (HDL) complex, has a mean size of 8–10 nm and a density of 1.063–1.21 g/ml. The HDL particle consists of a central core of esterified cholesterol with a surrounding monolayer of phospholipids,...

Biobank Study Of Severe Deficiency Of Vitamin D In Pulmonary Arterial Hypertension Patients

Vitamin D is produced in the skin by photochemical transformation of 7-dehydrocholesterol (7DHC) into pre-vitamin D and can also be absorbed from dietary intake. In blood 25 hydroxyvitamin D (25(OH)D) is the most abundant and studied form of vitamin D...

A New Blood Test Algorithm mPoA – Quantifying Biological Aging

People age at different rates determined by both their environment/ lifestyle and genetics. Biological aging is the gradual and progressive decline in body integrity that occurs over time eventually leading to loss of vitality or illness/ disability in some cases....

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