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Global Biobank Meta-analysis Initiative (GBMI) Connects Biobanks Together to Enable Better Studies of Genetic Disease

Global Biobank Meta-analysis Initiative (GBMI) Connects Biobanks Together to Enable Better Studies of Genetic...

In 2019, scientists at the Broad Institute of MIT and Harvard, together with colleagues at the University of Michigan and researchers around the world, founded the Global Biobank Meta-analysis Initiative (GBMI) to connect international biobanks in order to enable larger,...

Genetic Associations With Lung Function In A Korean Population

Lung function can be measured in terms of forced expiratory volume in one second (FEV1) and forced vital capacity (FVC); the total amount that can be exhaled after maximum inhale, as well as the ratio between the two. Genetic...

A Systems Approach To Cerebrospinal Fluid Analysis

Found in the brain and spinal cord, the cerebrospinal fluid (CSF) is a clear, colorless fluid with a total volume of about 125ml per person, produced by specialized neuroglia called ependymal cells, that acts as a buffer and cushioning solution. The brain...

T-GEN – A GWAS Method Incorporating Epigenetics

Junk DNA, black-box DNA, repeat elements, transposons, endogenous retroviruses, long non-coding RNAs are just some of the names for and elements of non-protein coding DNA that make up 99% of the human genome. Aside from structural elements such as telomeres, many “Junk...

Biobank Study Of Functional Lung Impairment And Lung Cancer Risk

Globally, cancer of the lung is the most common cause of cancer related mortality. It is also the most commonly diagnosed. Tobacco smoke is a well-known risk factor for the development of lung cancer. Smoking leads to lung impairment and conditions such...

Potential Targets For Opioid Addiction Treatment Uncovered By GWAS

The USA is in the midst of an opioid addiction crisis with overdoses having killed 47,600 people in 2017, according to the Centers for Disease Control and Prevention (CDC). Opioids such as OxyContin® and Vicodin® are used in pain medications and many...

23andMe Backed Study Reveals Genetic Risk Factors For Hyperemesis Gravidarum

Nausea and vomiting vary considerably in duration and severity in pregnancy but are common complaints . Hyperemesis gravidarum (HG) is a condition that occurs in 0.3–2% of pregnancies and is associated with maternal and fetal morbidity, which represents the...

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