Latest Research

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Learning From Human Bile – A Machine Intelligence Approach

The digestive fluid called bile is made up of acids, salts, fats, and the pigment bilirubin, stored and concentrated in the gall bladder, and produced by the liver. Protein is a significant component of bile, 5% of the dry...

Collagen Content Changes Detected By Raman Spectroscopy In Herniated Spinal Chord

In the spinal cord, the nucleus pulposus (NP) is the collagen rich core of the intervertebral discs. Intervertebral disc degeneration (IDD) is thought to be a major contributor to lower back pain, which the majority of people will experience...

How Do People In Nashville React To The Biobank Consent Process?

Gathering informed consent from participants is a pillar of biobanking. As ambitious biobanking projects such as All of US and UK biobank proliferate and become ever larger, the benefits and the potential risks for participants also grow. It is...
H3Africa biobanks and studies.

Biobanking Science: Lessons from African Biobanks

With the recent advances in genomic sequencing, proteomics and precision medicine, biobanks are becoming more prevalent around the world. So are large-scale population studies such as the UK Biobank. H3Africa Project and Biobanks The Human, Hereditary and Health in Africa (H3Africa)...
UK Biobank data used to study chronic diseases.

Biobanking Science: Disease Patterns in UK Biobank Data

The UK Biobank is one of the biggest biobanking projects in the world with samples and data from over 500,000 participants aged 40 to 69 years. UK Biobank participants allow doctors to take repeat physiological measurements such as blood...

COVID-19 Risk In Different Ethnic And Socioeconomic Groups Within UK Biobank

Socioeconomic and ethnic factors may influence the risk of viral infection. For example, both economic circumstances and cultural influences may impact the extent to which people can implement distancing measures, thus modifying their risk. The extent to which this...

Leptin Associated With Cognitive Impairment In Older Adults Scheduled For Surgery

Adipokines are cytokines secreted by adipose (fat) tissue. Their existence was first noted in 1994, with the discovery of leptin. This cytokine is known to suppress hunger, but also promotes atherosclerosis, endothelial dysfunction and inflammation. Another adipokine, adiponectin is...

WTAP Gene Polymorphisms Modify Risk Of Hepatoblastoma

Hepatoblastoma is a form of cancer that accounts for 80% of childhood liver cancers, but only 1% of childhood cancers in total. It usually presents between birth and three years of age. As it is a relatively rare tumour...

EU-CardioRNA COST Action Meetings Report Released

The European Cooperation in Science and Technology (COST Association) runs an EU-funded programme that encourages researchers and innovators to create research networks called COST Actions. The EU-CardioRNA COST Action, launched in 2018, is intended to promote transcriptomics research in...

Estrogen Receptor Isoforms Are Down-Regulated In Hepatocellular Carcinoma

Estrogen receptor alpha (ERΞ±) translocates to the nucleus and induces gene expression upon activation. The estrogen receptor is a target of US Food and Drug Administration FDA approved drugs such as the selective estrogen receptor degrader called Fulvestrant, which...

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