The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is part of the United States National Institutes of Health, which in turn is part of the Department of Health and Human Services.
The NIDDK Central Repository (NIDDK-CR) is a contract-supported centralized repository managed by two separate yet integrated components: the Data Repository and the Biorepository. These components work together to acquire, store, and distribute resources generated from large multicenter studies supported by NIDDK or that are within the research areas and mission of NIDDK. The mission of the NIDDK-CR is to facilitate sharing of resources for secondary uses, thus encouraging work by junior or established investigators, investigators with novel approaches, and others not included in current collaborations. Secondary research use helps to maximize research participants’ contributions and decreases duplicative sampling efforts, thereby increasing the scientific value and impact of the originating study.
Established in 2003, the NIDDK-CR has continually expanded its portfolio over the years, creating a valuable data resource with which researchers can rapidly validate clinical hypotheses and algorithms for clinical decision-making, and matched specimen collections, which are also advancing the development of prognostic variables, biomarkers, and therapeutics for diseases related to the mission of NIDDK. In 2022, NIDDK-CR relaunched its website, Resources for Research (R4R), featuring a streamlined approach to the request process and enhancements to support findability and accessibility of NIDDK resources.
