PROCURE Biobank

Biobank Description

The PROCURE multi-site Biobank has been created by a team of urologists, scientists and pathologists of four university hospitals from Quebec province, collecting biospecimens and clinical data of patients undergoing radical prostatectomy (RP) for their cancer and who are followed longitudinally during remission or recurrence of their disease.

From 2006 to 2013, the biobank enrolled 2007 men. Blood (serum, plasma, buffy coat), urine, and prostate tissues (frozen and FFPE) obtained at RP were banked. Clinico-pathological data were collected and registered in Advanced Tissue Management software database (ATiM) and updated periodically. Follow-up visits permitted blood and urine recollection. Clinical data (PSA value, recurrence, treatments) were updated for at least five years post-RP for 86% of the cohort.

In 2021, more than 10 500 collections of blood and urine have been registered, including 8 500 at follow-up visits. A majority of participants (87%) have provided additional samples after RP. A tissue microarray composed of benign and cancer tissue cores from 1637 participants was generated. Blood and tissue DNA along with RNA and histopathology of frozen vs fixed tissues confirmed the reliability and quality of this longitudinally banked material.

Biobank Ownership
University/Academic
International Collaboration
No
Sample/Data Access
Open to Applicants
Head/Director
Dr Alain Bergeron
Date Established
Certified by Accredited Body
Yes
Biobanking Network
CTRNet
Collection Information
Donor Count
1001 - 5000
Total Sample Quantity
50001 - 100000
Specimen Origin
Human - Adult
Materials
Tissue (frozen)
Tissue (FFPE)
DNA
RNA
Whole Blood
Plasma
Serum
Peripheral Blood Cells
Buffy Coat
Urine
Data Type
Donor Clinical Data
Followup Records
Medical Records
Pathology Records
Physiological/Biochemical Measurements
Quality Indicators
Biobanking Services
Contact Information
Research Institute of McGill University Health Centre, 1001 Decarie Blvd, Montreal (QC) , H4A 3J1, Canada
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