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David Orchard-Webb, PhD

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David is a consultant/medical writer for a number of ongoing healthcare initiatives including for Athla LLC/ HealthLabs, a discovery automation company for Big Data leveraging Big Compute. He has a number of years experience in academic R&D and healthcare related projects including the fields of oncology and immunotherapy.

Serum Uric Acid Predicts Kidney Cancer Incidence

According to the US Surveillance, Epidemiology, and End Results program, the outlook for kidney cancer patients is generally favourable with an overall...

PALB2 May Be A Risk Locus For Ovarian Cancer

According to US Surveillance, Epidemiology, and End Results (SEER), overall, the five year survival rate for ovarian cancer is 49%, however for...

Estrogen Receptor Isoforms Are Down-Regulated In Hepatocellular Carcinoma

Estrogen receptor alpha (ERα) translocates to the nucleus and induces gene expression upon activation. The estrogen receptor is a target of US...

Apolipoprotein E (APOE) Isoform Association With Aging In UK Biobank

The APOE (Apolipoprotein E) gene has three main isoforms known as APOE2, APOE3, and APOE4. The ε4 allele is thought to be...

Complement And Coagulation Disorders Associated With COVID-19

Recent structure based comparisons suggest that coronavirus proteins mimic at least 140 human proteins, including those in the complement and coagulation pathways....

Genetics Of Susceptibility To Viral Infection

The severity of infectious diseases vary from person to person partly due to individual genetic factors. This can shape genetics at the...

Markers Of “Immune Hot” Esophageal Adenocarcinoma

According to the US National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results Program (SEER), the incidence of adenocarcinoma of the esophagus...

COVID-19 Risk In Different Ethnic And Socioeconomic Groups Within UK Biobank

Socioeconomic and ethnic factors may influence the risk of viral infection. For example, both economic circumstances and cultural influences may impact the...

A Standardized Mega-Biobank Phenomic Library From The Million Veteran Program

Often International Classification of Diseases (ICD) codes are used as a proxy for clinical phenotypes, however their intended purpose is for billing,...

Mapping Existing Biobank Data To EHR Common Data Model Not Clean Or Straightforward

The Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) information synthesis approach transforms data contained within electronic health records (EHR) and...

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